Women in their late 40s and older are usually those who experience the clear and evident symptoms of the onset of this female phase of life. Zhi Bai di Huang wan is frequently given to menopausal women who are suffering from hot flashes and night sweats. It also contains herbs that help dispel heat and dampness such as Phellododen bark which according to traditional use may reduce edema and swelling as well. The ingredients in Zhi Bai di Huang wan address conditions connected with deficient liver and kidney Yin. This formula may also be suggested to someone who is fearful, frightened, emotional, insomnia and irritability.