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Huperzine A
Neurotransmitter Support
| Common Name:
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Huperzine
A
|
| Botanical Name:
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Huperzia
serrata
|
| Pin Yin Name:
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--
|
| Actions:
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Central
and peripheral nervous system
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| Origin
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China
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| SN1931 |
Huperzine A
Source Naturals
Huperzia serrata leaf standarized
extract
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Supplement Facts for 100 mcg Tablet
Serving Size: 1 Tablet |
| |
Amount |
%DV |
| Huperzine
A (Huperzia serrata leaf standardized
extract) |
100
mcg |
|
|
Other Ingredients: microcrystalline cellulose, and stearic
acid.
|
tablet
Form:
120
tablets per bottle |
$31.99 |
 |
Natural Support for Brain Function
Huperzine A is a plant alkaloid
derived from the Chinese club moss plant Huperzia
serrata. It has been found to protect
neurotransmitters in the brain. Specifically, it protects
acetylcholine, a messenger molecule in the central and peripheral
nervous system that is strongly involved in vital functions such as
cognition, concentration, and memory. Huperzine A is currently in phase III trials in China for the treatment of patients with Alzheimer's disease. The mechanism of action of huperzine A is suggested to be facilitated through the slow reversible inhibition of acetylcholinesterase.[1] Huperzine A is a natural compound extracted from the Chinese club moss Huperzia serrata. Worldwide studies have shown that Huperzine A supports learning and memory by protecting acetylcholine, a neurotransmitter that acts as a messenger molecule in the brain.[2] Huperzine A is being studied for potential use in treating Alzheimer disease.
Huperzine A is able to pass through the blood-brain barrier, and has great potential to promote alertness, cognitive function, focus and memory. Most clinical studies on this extract have involved
Alzheimer's patients; however, in one adolescent study, researchers found Huperzine A improved their memory and learning when consuming 100 mcg, twice per day for four weeks.[14] Huperzine A is a lesser known compound that has shown promise in improving memory. About 60% of those taking huperzine A in one study had moderate beneficial improvement in memory.[15]
It’s All About Balance
When people have loss of brain
function, insufficient messenger molecules, like the important
neurotransmitter acetylcholine, remain to do their jobs. It is
thought that in aging people, or people with compromised health,
that this
enzyme acetylcholinesterase does not keep balance in the brain but
instead wipes out too much acetylcholine. Huperzine A inhibits the
enzyme acetylcholinesterase (uh-SEE-tul-co-lin-ES-ter-ase). This
enzyme breaks down acetylcholine, a substance that plays an
important role in mental function. Huperzine A is what keeps the acetylcholinesterase in check, making
sure that enough messenger molecules remain at work. Huperzine A
protects the messenger molecules, the acetylcholine.
Heightened
Cholinergic Function
The cholinergic function is the
pathway or circuit that neurons travel to relay signals, which in
turn is how memory and cognition work. Slight cholinergic
deterioration plays a role in benign memory changes associated with
healthy aging, but it is also a factor of more severe
cognitive declines. Brain choline decreases naturally with
age, however Huperzine A appears to protect the number, size and
function of cholinergic neurons. It has been shown to affect the
survival and outgrowth of central cholinergic neurons.
All Ages Can Benefit
Worldwide studies have shown the
efficacy of Huperzine A in memory and learning in adolescents,
particularly benefiting students in scores of accumulation,
recognition, association, factual memory, and recitations.
References:
Furley, M. et al. (2000) Cholinergic
Enhancement and Increased Selectivity of Perceptual
Processing During Working Memory. Science
290 pp 2315-2319.
Sun, Q et al. (1999) Huperzine-A
capsules enhance memory and learning performance in 34 pairs of
matched adolescent students. Hongguo Yao Li
Xue Bao 20(7) 601-603.
Cohen, B. et al. (1995) Decreased
Brain Choline Uptake in Older Adults. Journal
of the American
Medical Association 274(11)
pp 902-907. Tang, L. et al (2005) Effects of Huperzine A on
secretion of nerve growth factor in cultured rat cortical astrocytes
and neurite outgrowth in rat PC12 cells Acta
Pharmacologica Sinica 26(6) pp 673-678.
[1]http://www.raysahelian.com/huperzinea.html
[2] http://www.evitamins.com/product.asp?pid=10426
[3] http://www.drugs.com/npc/huperzine-a.html
[14] http://www.naturalproductsinsider.com/articles/
[15] http://www.doctorshealthsolution.com/
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Please note: Definitions of
the following forms which are products are sold in.
| Powdered Concentrates |
5:1 Ratio of an herb in
Powder form. 100 gram container size.(3.5 oz)
This has been processed, and usually has dextrin added. |
| Powdered Herb |
This is the herb, root,
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fine mesh which usually can be put into capsules. Most of the Powders herbs are in a 1 pound size, unless otherwise
noted. |
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This the herb, root,
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general about 1/4 thick. Size of herbs are 1 pound containers |
| Whole |
In very rare occasion
herbs are whole, for example the Reishi Mushroom,
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| Teapills |
These are small pills
which have already been formulated and made into small pills.
Usually the size of small peas. The teapills are swallowed whole.
The formula is usually based on Ancient Chinese Medicine. |
| Capsules |
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An extract is produced by adding alcohol to
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| Loose Leaf |
The herb is not in a teabag. It is
loose in the packaging. Sizes of the leaf vary from 1/4 inch
to 1 inch depending on herb and brand. |
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